One & Done?
Exploring Psilocybin's Long-Term Impact
It’s time for another deep dive into the world of psilocybin research!
This week, we’re shining a spotlight on exciting research published in Scientific Reports.
This study brought a star-studded team of psychedelic researchers together to dig into a mystery.
The subject of their investigation?
The long-term effects of a single, high-dose psilocybin experience on our emotions, moods, and brain function.
Interested? Let’s dive in!

The Study at a Glance
Researchers embarked on a fascinating adventure with twelve volunteers.
They wanted to see how psilocybin, the “magic” behind magic mushrooms, could change moods, feelings, and brain activities over time.
Before, After, and Beyond:
Volunteers were observed before, one week after, and even a month following their psilocybin experience.
Mindful Monitoring
Through brain scans (fMRI) and personal reflections, the team tracked the changes each participant experienced.
The Perfect Dose
Each volunteer received 25mg of psilocybin per 70 kg of body weight, a dose carefully chosen based on Roland Griffiths’ exploration into the mystical realms of mushrooms.

The Results 🔬
1. Less Negative Emotions
A week after their psilocybin journey, participants experienced a noticeable dip in negative emotions.
Brain scans showed a calmer amygdala, suggesting a more balanced emotional response.
An entire month later, participants still felt an uplift in their mood, with a significant drop in overall anxiety levels.
Thirty days post-psilocybin, loved ones observed the volunteers as more considerate, responsible, and happier.

Final Thoughts
While these findings are promising, the study’s limitations remind us that this is just the beginning of a longer journey of discovery.
This study is yet another testament to psilocybin’s potential to foster long-term positive transformations in our emotional and mental landscapes.
Until next time,
Keep Watering Your Mind!💧🧠
